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DL

David R. Liu

Broad Institute US

0000-0002-9943-7557

375

Publications

77,384

Citations

124

H-Index

280

i10-Index

27.58

2yr Mean Cite

-

Cite/Paper

Data combined from OpenAlex . OA = OpenAlex S2 = Semantic Scholar

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Publication & Citation Trends

Most Cited Works

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1 OA

Mamta Tahiliani, Kian Peng Koh, Yinghua Shen, William A. Pastor, Hozefa S. Bandukwala +6 more

Science 2009

5,786

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage OA

Alexis C. Komor, Y. Bill Kim, Michael S. Packer, John A. Zuris, David R. Liu

Nature 2016

5,316

Search-and-replace genome editing without double-strand breaks or donor DNA OA

Andrew V. Anzalone, Peyton B. Randolph, Jessie R. Davis, Alexander A. Sousa, Luke W. Koblan +6 more

Nature 2019

4,500

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage OA

Nicole M. Gaudelli, Alexis C. Komor, Holly A. Rees, Michael S. Packer, Ahmed H. Badran +2 more

Nature 2017

4,109

Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors

Andrew V. Anzalone, Luke W. Koblan, David R. Liu

Nature Biotechnology 2020

2,237

Publications

374 total

Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors

Andrew V. Anzalone, Luke W. Koblan, David R. Liu - Nature Biotechnology, 2020

Cited by 2,237 OpenAlex

Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity PDF

Michelle F. Richter, Kevin T. Zhao, Elliot O. Eton, Audronė Lapinaitė, Gregory A. Newby et al. - Nature Biotechnology, 2020

Cited by 1,007 OpenAlex

Search-and-replace genome editing without double-strand breaks or donor DNA PDF

Andrew V. Anzalone, Peyton B. Randolph, Jessie R. Davis, Alexander A. Sousa, Luke W. Koblan et al. - Nature, 2019

Cited by 4,500 OpenAlex

CRISPResso2 provides accurate and rapid genome editing sequence analysis

Kendell Clement, Holly A. Rees, Matthew C. Canver, Jason M. Gehrke, Rick Farouni et al. - Nature Biotechnology, 2019

Cited by 1,770 OpenAlex

Base editing: precision chemistry on the genome and transcriptome of living cells PDF

Holly A. Rees, David R. Liu - Nature Reviews Genetics, 2018

Cited by 1,665 OpenAlex

Evolved Cas9 variants with broad PAM compatibility and high DNA specificity

Johnny H. Hu, Shannon M. Miller, Maarten H. Geurts, Weixin Tang, Liwei Chen et al. - Nature, 2018

Cited by 1,593 OpenAlex

Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction PDF

Luke W. Koblan, Jordan L. Doman, Christopher Wilson, Jonathan M. Levy, Tristan Tay et al. - Nature Biotechnology, 2018

Cited by 973 OpenAlex

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage PDF

Nicole M. Gaudelli, Alexis C. Komor, Holly A. Rees, Michael S. Packer, Ahmed H. Badran et al. - Nature, 2017

Cited by 4,109 OpenAlex

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage PDF

Alexis C. Komor, Y. Bill Kim, Michael S. Packer, John A. Zuris, David R. Liu - Nature, 2016

Cited by 5,316 OpenAlex

CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes

Alexis C. Komor, Ahmed H. Badran, David R. Liu - Cell, 2016

Cited by 1,016 OpenAlex

Research Topics

CRISPR and Genetic Engineering (176) RNA and protein synthesis mechanisms (113) Advanced biosensing and bioanalysis techniques (85) RNA regulation and disease (46) Virus-based gene therapy research (44)

Frequent Co-Authors

LU

Luke W. Koblan

4 joint publications

HO

Holly A. Rees

4 joint publications

AL

Alexis C. Komor

3 joint publications

MI

Michael S. Packer

3 joint publications

CH

Christopher Wilson

3 joint publications

GR

Gregory A. Newby

3 joint publications

Affiliations

Broad Institute

US 2026 - 2013

Queens College, CUNY

US 2025 - 2025

Scripps Research Institute

US 2000 - 1999

Boston Children's Hospital

US 2018 - 2018

Beth Israel Deaconess Medical Center

US 2017 - 2017

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