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Alexis C. Komor

University of California San Diego US

ORCID iD 0000-0001-5043-0998
70
Publications
14,998
Citations
23
H-Index
35
i10-Index
7.36
2yr Mean Cite
-
Cite/Paper
Data combined from OpenAlex + Semantic Scholar. OA = OpenAlex S2 = Semantic Scholar
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Publication & Citation Trends

Most Cited Works

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage OA
Alexis C. Komor, Y. Bill Kim, Michael S. Packer, John A. Zuris, David R. Liu
Nature 2016
5,316
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage OA
Nicole M. Gaudelli, Alexis C. Komor, Holly A. Rees, Michael S. Packer, Ahmed H. Badran +2 more
Nature 2017
4,109
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
Alexis C. Komor, Ahmed H. Badran, David R. Liu
Cell 2016
1,016
Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions OA
Y. Bill Kim, Alexis C. Komor, Jonathan M. Levy, Michael S. Packer, Kevin T. Zhao +1 more
Nature Biotechnology 2017
782
Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity OA
Alexis C. Komor, Kevin T. Zhao, Michael S. Packer, Nicole M. Gaudelli, Amanda L. Waterbury +4 more
Science Advances 2017
773

Publications

70 total

Precise, minimally evolved adenine base editors generated through mutation reversion analysis.

Mallory Evanoff, Sanjana Korpal, Zachary D Krill, Quinn T. Cowan, Alexis C. Komor - Nature Biotechnology, 2026
Cited by 0 Semantic Scholar

Precision genome editing with DNA base editors

S. Mawson, Kara Dunne-Dombrink, Benjamin R. Pollak, Alexis C. Komor - Nature Reviews Methods Primers, 2026
Cited by 0 Semantic Scholar

Highly efficient expression of DNA-peptide conjugates in growth-arrested cells

Zulfiqar Y Mohamedshah, Chih-Chin Chi, Ember M. Tota, Alexis C. Komor, Neal K. Devaraj - Nature Communications, 2026
Cited by 0 Semantic Scholar

Genome editing with programmable base editors in human cells.

Nicola R B Osgood, Natalie M Zawalick, C. Sawyer, Quinn T. Cowan, Sifeng Gu - Methods in Enzymology, 2025
Cited by 1 Semantic Scholar

CTRL Enables Gene-Specific RNA Regulation Using CRISPR-Cas7-11.

Tianqi Wang, Daniel J. Brogan, Natalie M Zawalick, Fangying Chen, Yeran Mkrtchian - ACS Synthetic Biology, 2025
Cited by 0 Semantic Scholar

Personalized Gene Editing to Treat an Inborn Error of Metabolism.

A. Gropman, Alexis C. Komor - New England Journal of Medicine, 2025
Cited by 4 Semantic Scholar

Elucidating the genetic mechanisms governing cytosine base editing outcomes through CRISPRi screens

Sifeng Gu, Z. Bodai, Rachel A. Anderson, Hei Yu Annika So, Quinn T. Cowan - Nature Communications, 2025
Cited by 5 Semantic Scholar

Precision genome editing and in-cell measurements of oxidative DNA damage repair enable functional and mechanistic characterization of cancer-associated MUTYH variants

Carlos A Vasquez, Nicola R B Osgood, Marcanthony U Zepeda, Dominika K Sandel, Quinn T. Cowan - Nucleic Acids Research, 2025
Cited by 4 Semantic Scholar

Functional EPAS1/HIF2A missense variant is associated with hematocrit in Andean highlanders OA

Elijah S Lawrence, W. Gu, R. Bohlender, C. Anza-Ramirez, Amy M. Cole - Science Advances, 2024
Cited by 31 Semantic Scholar

Development of multiplexed orthogonal base editor (MOBE) systems

Quinn T. Cowan, Sifeng Gu, Wanjun Gu, Brodie L. Ranzau, T. Simonson - Nature Biotechnology, 2024
Cited by 16 Semantic Scholar

Research Topics

CRISPR and Genetic Engineering (43) RNA and protein synthesis mechanisms (22) RNA regulation and disease (18) Metal complexes synthesis and properties (14) Advanced biosensing and bioanalysis techniques (8)

Frequent Co-Authors

DA
David R. Liu
8 joint publications
AH
Ahmed H. Badran
5 joint publications
MI
Michael S. Packer
4 joint publications
Y.
Y. Bill Kim
3 joint publications
JA
Jacqueline K. Barton
3 joint publications
NI
Nicole M. Gaudelli
2 joint publications

Affiliations

Broad Institute
US 2018 - 2016
California Institute of Technology
US 2014 - 2011
Howard Hughes Medical Institute
US 2018 - 2016
Harvard University
US 2018 - 2016
University of California, San Diego
US 2026 - 2017

External Profiles

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