article Closed Access EN 2018-07-20

Sepsis-related coagulopathy

Zhongguo xiaoer jijiu yixue, Vol. 25, Issue 7, pp. 490–493 (2018)

China Medical University

DOI: 10.3760/cma.j.issn.1673-4912.2018.07.003

Abstract

Disseminated intravascular coagulation(DIC) remains a challenging syndrome for intensivists, as the markers enabling its identification are lacking, and the treatment is patient dependent.The process underlying DIC is a complex interlinked framework of proteases of both the coagulation and inflammatory cascades, thus explaining the difficulty in DIC management.Identification can be accomplished with scoring systems such as the DIC score, and treatment begins with identification and treatment of the underlying infectious cause.Supportive care and correction of coagulopathies should be provided simultaneously to prevent irreversible end-organ injury and DIC progression. Key words: Sepsis; Disseminated intravascular coagulation; Coagulopathy

Topics

Sepsis Diagnosis and Treatment 0.93 Trauma, Hemostasis, Coagulopathy, Resuscitation 0.93

Field: Medicine · Subfield: Epidemiology

Keywords

Coagulopathy,Disseminated intravascular coagulation,Medicine,Sepsis,Intensive care medicine,Systemic inflammatory response syndrome,Organ dysfunction,Coagulation,Multiple organ dysfunction syndrome,Identification (biology)