Dustin S. Siegel
0009-0008-1365-0287
Publication & Citation Trends
Most Cited Works
Publications
42 total
Prodrugs of a 1′-CN-4-Aza-7,9-dideazaadenosine <i>C</i>-Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV PDF
Cited by 84
OpenAlex
Discovery of the pan-genotypic hepatitis C virus NS3/4A protease inhibitor voxilaprevir (GS-9857): A component of Vosevi®
Cited by 85
OpenAlex
Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease PDF
Cited by 1,507
OpenAlex
Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle PDF
Cited by 77
OpenAlex
Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses PDF
Cited by 1,625
OpenAlex
Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-<i>f</i>][triazin-4-amino] Adenine <i>C</i>-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses PDF
Cited by 659
OpenAlex
GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses PDF
Cited by 511
OpenAlex
Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys PDF
Cited by 1,586
OpenAlex
Research Topics
Viral gastroenteritis research and epidemiology
(11)
Respiratory viral infections research
(10)
Synthetic Organic Chemistry Methods
(8)
Viral Infections and Outbreaks Research
(6)
Chemical synthesis and alkaloids
(6)
Frequent Co-Authors
Affiliations
Public Health Department
IIT@MIT
Gilead Sciences (United States)
Massachusetts Institute of Technology