Richard L. Mackman
0000-0001-8861-7205
Publication & Citation Trends
Most Cited Works
Publications
135 total
Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice PDF
Cited by 81
OpenAlex
Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets PDF
Cited by 124
OpenAlex
Prodrugs of a 1′-CN-4-Aza-7,9-dideazaadenosine <i>C</i>-Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV PDF
Cited by 84
OpenAlex
Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease PDF
Cited by 1,507
OpenAlex
Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses PDF
Cited by 1,625
OpenAlex
Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-<i>f</i>][triazin-4-amino] Adenine <i>C</i>-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses PDF
Cited by 659
OpenAlex
GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses PDF
Cited by 511
OpenAlex
Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys PDF
Cited by 1,586
OpenAlex
Research Topics
HIV/AIDS drug development and treatment
(27)
Respiratory viral infections research
(21)
SARS-CoV-2 and COVID-19 Research
(20)
Viral gastroenteritis research and epidemiology
(18)
Crystallization and Solubility Studies
(16)
Frequent Co-Authors
Affiliations
University of California, San Francisco
Vanderbilt University
University of Cambridge
University of Florida
Public Health Department