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PH

Pengxiang Huang

Baylor College of Medicine US

37
Publications
4,252
Citations
18
H-Index
19
i10-Index
1.17
2yr Mean Cite
-
Cite/Paper
Data combined from OpenAlex . OA = OpenAlex S2 = Semantic Scholar
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Publication & Citation Trends

Most Cited Works

Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA OA
Vikas Chandra, Pengxiang Huang, Lora Hamuro, Srilatha Raghuram, Yongjun Wang +2 more
Nature 2008
815
Identification of heme as the ligand for the orphan nuclear receptors REV-ERBα and REV-ERBβ OA
Srilatha Raghuram, Keith R. Stayrook, Pengxiang Huang, Pamela M. Rogers, Amanda K. Nosie +5 more
Nature Structural & Molecular Biology 2007
554
Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity
Jun R. Huh, Monica Leung, Pengxiang Huang, Daniel A. Ryan, Michael R. Krout +12 more
Nature 2011
534
Structural Overview of the Nuclear Receptor Superfamily: Insights into Physiology and Therapeutics OA
Pengxiang Huang, Vikas Chandra, Fraydoon Rastinejad
Annual Review of Physiology 2010
518
Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling OA
Pengxiang Huang, Daniel Nedelcu, Miyako Watanabe, Cindy Y. Jao, Youngchang Kim +2 more
Cell 2016
382

Publications

37 total

Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitors PDF

Xiangdong Lv, Xuan Lu, Jin Cao, Qin Luo, Yao Ding et al. - Science, 2023
Cited by 100 OpenAlex

Ceramides and sphingosine-1-phosphate mediate the distinct effects of M1/M2-macrophage infusion on liver recovery after hepatectomy PDF

Hang Sun, Shibo Sun, Gang Chen, Haorong Xie, Sheng Yu et al. - Cell Death and Disease, 2021
Cited by 39 OpenAlex

Structural Basis of Smoothened Activation in Hedgehog Signaling PDF

Pengxiang Huang, Sanduo Zheng, Bradley M. Wierbowski, Youngchang Kim, Daniel Nedelcu et al. - Cell, 2018
Cited by 188 OpenAlex

Structural Basis of Smoothened Activation in Hedgehog Signaling PDF

Pengxiang Huang, Sanduo Zheng, Bradley M. Wierbowski, Youngchang Kim, Daniel Nedelcu et al. - Cell, 2018
Cited by 52 OpenAlex

Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling PDF

Pengxiang Huang, Daniel Nedelcu, Miyako Watanabe, Cindy Y. Jao, Youngchang Kim et al. - Cell, 2016
Cited by 382 OpenAlex

Identification of Natural RORγ Ligands that Regulate the Development of Lymphoid Cells PDF

Fabio R. Santori, Pengxiang Huang, Serge A. van de Pavert, Eugene F. Douglass, David J. Leaver et al. - Cell Metabolism, 2015
Cited by 228 OpenAlex

Multidomain integration in the structure of the HNF-4α nuclear receptor complex PDF

Vikas Chandra, Pengxiang Huang, Nalini Potluri, Dalei Wu, Youngchang Kim et al. - Nature, 2013
Cited by 205 OpenAlex

Understanding nuclear receptor form and function using structural biology PDF

Fraydoon Rastinejad, Pengxiang Huang, Vikas Chandra, Sepideh Khorasanizadeh - Journal of Molecular Endocrinology, 2013
Cited by 201 OpenAlex

Retinoic Acid Actions through Mammalian Nuclear Receptors

Pengxiang Huang, Vikas Chandra, Fraydoon Rastinejad - Chemical Reviews, 2013
Cited by 165 OpenAlex

Identification of Potent and Selective Diphenylpropanamide RORγ Inhibitors PDF

Jun R. Huh, Erika Englund, Hang Wang, Ruili Huang, Pengxiang Huang et al. - ACS Medicinal Chemistry Letters, 2012
Cited by 64 OpenAlex

Research Topics

Liver Disease Diagnosis and Treatment (6) Sphingolipid Metabolism and Signaling (6) Retinoids in leukemia and cellular processes (6) Genomics and Chromatin Dynamics (4) Epigenetics and DNA Methylation (4)

Frequent Co-Authors

FR
Fraydoon Rastinejad
10 joint publications
VI
Vikas Chandra
5 joint publications
YO
Youngchang Kim
4 joint publications
SE
Sepideh Khorasanizadeh
3 joint publications
DA
Dan R. Littman
3 joint publications
DA
Daniel Nedelcu
3 joint publications

Affiliations

Fujian Medical University
CN 2025 - 2024
National Renewable Energy Laboratory
US 2025 - 2025
Harvard University
US 2022 - 2016
Baylor College of Medicine
US 2026 - 2023
Sanford Burnham Prebys Medical Discovery Institute
US 2015 - 2011

External Profiles

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