Xiao-Su Pan

St George's, University of London GB

Publications

2,634

Citations

H-Index

i10-Index

2.2

2yr Mean Cite

Cite/Paper

Data combined from OpenAlex . OA = OpenAlex S2 = Semantic Scholar

Verify on Google Scholar

Publication & Citation Trends

Most Cited Works

Involvement of topoisomerase IV and DNA gyrase as ciprofloxacin targets in Streptococcus pneumoniae OA

Xiao-Su Pan, Jane E. Ambler, Shaheen Mehtar, L. Mark Fisher

Antimicrobial Agents and Chemotherapy 1996

437

Structural insight into the quinolone–DNA cleavage complex of type IIA topoisomerases

Ivan Laponogov, Maninder K. Sohi, Dennis A. Veselkov, Xiao-Su Pan, Ritica Sawhney +4 more

Nature Structural & Molecular Biology 2009

292

Mycobacterium tuberculosis DNA Gyrase: Interaction with Quinolones and Correlation with Antimycobacterial Drug Activity OA

Alexandra Aubry, Xiao-Su Pan, L. Mark Fisher, Vincent Jarlier, Emmanuelle Cambau

Antimicrobial Agents and Chemotherapy 2004

234

Targeting of DNA gyrase in Streptococcus pneumoniae by sparfloxacin: selective targeting of gyrase or topoisomerase IV by quinolones OA

Xiao-Su Pan, L. Mark Fisher

Antimicrobial Agents and Chemotherapy 1997

231

DNA Gyrase and Topoisomerase IV Are Dual Targets of Clinafloxacin Action in Streptococcus pneumoniae OA

Xiao-Su Pan, L. Mark Fisher

Antimicrobial Agents and Chemotherapy 1998

208

Publications

49 total

Structure of an ‘open’ clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport PDF

Ivan Laponogov, Dennis A. Veselkov, Isabelle Crevel, Xiao-Su Pan, L. Mark Fisher et al. - Nucleic Acids Research, 2013

Cited by 66 OpenAlex

Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases PDF

Ivan Laponogov, Xiao-Su Pan, Dennis A. Veselkov, Katherine McAuley, L. Mark Fisher et al. - PLoS ONE, 2010

Cited by 172 OpenAlex

Structural insight into the quinolone–DNA cleavage complex of type IIA topoisomerases

Ivan Laponogov, Maninder K. Sohi, Dennis A. Veselkov, Xiao-Su Pan, Ritica Sawhney et al. - Nature Structural & Molecular Biology, 2009

Cited by 292 OpenAlex

Target specificity of the new fluoroquinolone besifloxacin in Streptococcus pneumoniae, Staphylococcus aureus and Escherichia coli PDF

Emmanuelle Cambau, Stéphanie Matrat, Xiao-Su Pan, Romain Roth dit Bettoni, C. Corbel et al. - Journal of Antimicrobial Chemotherapy, 2009

Cited by 82 OpenAlex

Probing the Differential Interactions of Quinazolinedione PD 0305970 and Quinolones with Gyrase and Topoisomerase IV

Xiao-Su Pan, Katherine A. Gould, L. Mark Fisher - Antimicrobial Agents and Chemotherapy, 2009

Cited by 62 OpenAlex

Novel Symmetric and Asymmetric DNA Scission Determinants for Streptococcus pneumoniae Topoisomerase IV and Gyrase Are Clustered at the DNA Breakage Site PDF

Elisabetta Leo, Katherine A. Gould, Xiao-Su Pan, Giovanni Capranico, Mark R. Sanderson et al. - Journal of Biological Chemistry, 2005

Cited by 51 OpenAlex

Mycobacterium tuberculosis DNA Gyrase: Interaction with Quinolones and Correlation with Antimycobacterial Drug Activity PDF

Alexandra Aubry, Xiao-Su Pan, L. Mark Fisher, Vincent Jarlier, Emmanuelle Cambau - Antimicrobial Agents and Chemotherapy, 2004

Cited by 234 OpenAlex

Cleavable-Complex Formation by Wild-Type and Quinolone-Resistant Streptococcus pneumoniae Type II Topoisomerases Mediated by Gemifloxacin and Other Fluoroquinolones PDF

Genoveva Yagüe, Julia E. Morris, Xiao-Su Pan, Katherine A. Gould, L. Mark Fisher - Antimicrobial Agents and Chemotherapy, 2002

Cited by 54 OpenAlex

Quinolone Resistance Mutations in Streptococcus pneumoniae GyrA and ParC Proteins: Mechanistic Insights into Quinolone Action from Enzymatic Analysis, Intracellular Levels, and Phenotypes of Wild-Type and Mutant Proteins PDF

Xiao-Su Pan, Genoveva Yagüe, L. Mark Fisher - Antimicrobial Agents and Chemotherapy, 2001

Cited by 69 OpenAlex

Engineering the Specificity of Antibacterial Fluoroquinolones: Benzenesulfonamide Modifications at C-7 of Ciprofloxacin Change Its Primary Target in Streptococcus pneumoniae from Topoisomerase IV to Gyrase PDF

Fabiana L. Alovero, Xiao-Su Pan, Julia E. Morris, Rubén H. Manzo, L. Mark Fisher - Antimicrobial Agents and Chemotherapy, 2000

Cited by 115 OpenAlex

Research Topics

Cancer therapeutics and mechanisms (40) Antibiotics Pharmacokinetics and Efficacy (22) Antibiotic Resistance in Bacteria (17) Neutropenia and Cancer Infections (11) Pneumonia and Respiratory Infections (6)

Frequent Co-Authors

L. Mark Fisher

15 joint publications

Mark R. Sanderson

4 joint publications

Ivan Laponogov

3 joint publications

Dennis A. Veselkov

3 joint publications

Katherine A. Gould

3 joint publications

Katherine McAuley

2 joint publications

Affiliations

University of London

GB 2004 - 1998

St George's Hospital

GB 2004 - 1996

Hohai University

CN 2024 - 2024

St George's, University of London

GB 2025 - 1998

King's College London

GB 2023 - 2013

External Profiles

OpenAlex Profile Search Semantic Scholar Google Scholar

Share Profile

Back to Researchers

Xiao-Su Pan

Publication & Citation Trends

Most Cited Works

Publications

Structure of an ‘open’ clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport PDF

Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases PDF

Structural insight into the quinolone–DNA cleavage complex of type IIA topoisomerases

Target specificity of the new fluoroquinolone besifloxacin in Streptococcus pneumoniae, Staphylococcus aureus and Escherichia coli PDF

Probing the Differential Interactions of Quinazolinedione PD 0305970 and Quinolones with Gyrase and Topoisomerase IV

Novel Symmetric and Asymmetric DNA Scission Determinants for Streptococcus pneumoniae Topoisomerase IV and Gyrase Are Clustered at the DNA Breakage Site PDF

<i>Mycobacterium tuberculosis</i> DNA Gyrase: Interaction with Quinolones and Correlation with Antimycobacterial Drug Activity PDF

Cleavable-Complex Formation by Wild-Type and Quinolone-Resistant <i>Streptococcus pneumoniae</i> Type II Topoisomerases Mediated by Gemifloxacin and Other Fluoroquinolones PDF

Quinolone Resistance Mutations in <i>Streptococcus pneumoniae</i> GyrA and ParC Proteins: Mechanistic Insights into Quinolone Action from Enzymatic Analysis, Intracellular Levels, and Phenotypes of Wild-Type and Mutant Proteins PDF

Engineering the Specificity of Antibacterial Fluoroquinolones: Benzenesulfonamide Modifications at C-7 of Ciprofloxacin Change Its Primary Target in <i>Streptococcus pneumoniae</i> from Topoisomerase IV to Gyrase PDF

Research Topics

Frequent Co-Authors

Affiliations

External Profiles

Share Profile

Xiao-Su Pan

Publication & Citation Trends

Most Cited Works

Publications

Research Topics

Frequent Co-Authors

Affiliations

External Profiles

Share Profile

Journal Details

Join JournalsHub

Welcome Back