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VJ

Veli‐Pekka Jaakola

Bone Therapeutics BE

ORCID iD 0000-0003-2943-6417
51
Publications
4,044
Citations
21
H-Index
30
i10-Index
20.0
2yr Mean Cite
-
Cite/Paper
Data combined from OpenAlex . OA = OpenAlex S2 = Semantic Scholar
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Publication & Citation Trends

Most Cited Works

The 2.6 Angstrom Crystal Structure of a Human A <sub>2A</sub> Adenosine Receptor Bound to an Antagonist OA
Veli‐Pekka Jaakola, Mark T. Griffith, Michael A. Hanson, Vadim Cherezov, Ellen Y. T. Chien +3 more
Science 2008
1,743
A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor OA
Michael A. Hanson, Vadim Cherezov, Mark T. Griffith, C. Roth, Veli‐Pekka Jaakola +4 more
Structure 2008
938
Structure-Based Discovery of Novel Chemotypes for Adenosine A<sub>2A</sub>Receptor Antagonists OA
Vsevolod Katritch, Veli‐Pekka Jaakola, J. Robert Lane, Judy Lin, Adriaan P. IJzerman +4 more
Journal of Medicinal Chemistry 2010
242
Structure of complement factor H carboxyl‐terminus reveals molecular basis of atypical haemolytic uremic syndrome OA
T. Sakari Jokiranta, Veli‐Pekka Jaakola, Markus J. Lehtinen, Maria Pärepalo, Seppo Meri +1 more
The EMBO Journal 2006
157
Designing Facial Amphiphiles for the Stabilization of Integral Membrane Proteins
Qinghai Zhang, Xingquan Ma, Andrew B. Ward, Wen‐Xu Hong, Veli‐Pekka Jaakola +3 more
Angewandte Chemie International Edition 2007
114

Publications

51 total

Accelerating GPCR Drug Discovery With Conformation-Stabilizing VHHs PDF

Toon Laeremans, Zara A. Sands, Pieter Claes, Ann De Blieck, Stéphane De Cesco et al. - Frontiers in Molecular Biosciences, 2022
Cited by 43 OpenAlex

Structural basis of species-selective antagonist binding to the succinate receptor

Matthias Haffke, Dominique Fehlmann, Gabriele Rummel, Jacques Boivineau, Myriam Duckely et al. - Nature, 2019
Cited by 92 OpenAlex

Functional reconstitution of human equilibrative nucleoside transporter-1 into styrene maleic acid co-polymer lipid particles PDF

Shahid Rehan, Ville O. Paavilainen, Veli‐Pekka Jaakola - Biochimica et Biophysica Acta (BBA) - Biomembranes, 2017
Cited by 33 OpenAlex

Defining thermostability of membrane proteins by western blotting PDF

Yashwanth Ashok, Rahul Nanekar, Veli‐Pekka Jaakola - Protein Engineering Design and Selection, 2015
Cited by 34 OpenAlex

Structure-Based Discovery of Novel Chemotypes for Adenosine A<sub>2A</sub>Receptor Antagonists PDF

Vsevolod Katritch, Veli‐Pekka Jaakola, J. Robert Lane, Judy Lin, Adriaan P. IJzerman et al. - Journal of Medicinal Chemistry, 2010
Cited by 242 OpenAlex

Ligand Binding and Subtype Selectivity of the Human A2A Adenosine Receptor PDF

Veli‐Pekka Jaakola, J. Robert Lane, Judy Lin, Vsevolod Katritch, Adriaan P. IJzerman et al. - Journal of Biological Chemistry, 2010
Cited by 92 OpenAlex

Structural features of adenosine receptors: From crystal to function

Henni Piirainen, Yashwanth Ashok, Rahul Nanekar, Veli‐Pekka Jaakola - Biochimica et Biophysica Acta (BBA) - Biomembranes, 2010
Cited by 64 OpenAlex

The crystallographic structure of the human adenosine A2A receptor in a high-affinity antagonist-bound state: implications for GPCR drug screening and design

Veli‐Pekka Jaakola, Adriaan P. IJzerman - Current Opinion in Structural Biology, 2010
Cited by 49 OpenAlex

The 2.6 Angstrom Crystal Structure of a Human A <sub>2A</sub> Adenosine Receptor Bound to an Antagonist PDF

Veli‐Pekka Jaakola, Mark T. Griffith, Michael A. Hanson, Vadim Cherezov, Ellen Y. T. Chien et al. - Science, 2008
Cited by 1,743 OpenAlex

A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor PDF

Michael A. Hanson, Vadim Cherezov, Mark T. Griffith, C. Roth, Veli‐Pekka Jaakola et al. - Structure, 2008
Cited by 938 OpenAlex

Research Topics

Receptor Mechanisms and Signaling (34) Adenosine and Purinergic Signaling (15) Neuropeptides and Animal Physiology (11) Lipid Membrane Structure and Behavior (9) Monoclonal and Polyclonal Antibodies Research (7)

Frequent Co-Authors

RA
Raymond C. Stevens
7 joint publications
AD
Adriaan P. IJzerman
4 joint publications
MA
Mark T. Griffith
3 joint publications
MI
Michael A. Hanson
3 joint publications
EL
Ellen Y. T. Chien
3 joint publications
J.
J. Robert Lane
3 joint publications

Affiliations

Scripps Research Institute
US 2010 - 2007
Novartis (Switzerland)
CH 2019 - 2015
University of Helsinki
FI 2006 - 2000
University of Turku
FI 1999 - 1999
Australian Regenerative Medicine Institute
AU 2023 - 2023

External Profiles

OpenAlex Profile Search Semantic Scholar ORCID Profile Google Scholar

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