Keito Hoshitsuki

University of Pittsburgh US

0000-0002-6723-0711

Publications

1,000

Citations

H-Index

i10-Index

6.83

2yr Mean Cite

True

Cite/Paper

Data combined from OpenAlex + Semantic Scholar. OA = OpenAlex S2 = Semantic Scholar

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Publication & Citation Trends

Most Cited Works

NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity OA

Takaya Moriyama, Rina Nishii, Virginia Pérez-Andreu, Wenjian Yang, Federico Antillón‐Klussmann +29 more

Nature Genetics 2016

464

Massively parallel variant characterization identifiesNUDT15alleles associated with thiopurine toxicity OA

Chase C. Suiter, Takaya Moriyama, Kenneth A. Matreyek, Wentao Yang, Emma Rose Scaletti +27 more

Proceedings of the National Academy of Sciences 2020

139

Clinical Pharmacogenetics Implementation Consortium Guideline for the Use of Aminoglycosides Based on MT‐RNR1 Genotype OA

John McDermott, Joshua Wolf, Keito Hoshitsuki, Rachel Huddart, Kelly E. Caudle +7 more

Clinical Pharmacology & Therapeutics 2021

103

Molecular basis of ETV6-mediated predisposition to childhood acute lymphoblastic leukemia OA

Rina Nishii, Rebekah Baskin-Doerfler, Wentao Yang, Ninad Oak, Xujie Zhao +24 more

Blood 2020

Glibenclamide Produces Region-Dependent Effects on Cerebral Edema in a Combined Injury Model of Traumatic Brain Injury and Hemorrhagic Shock in Mice

Ruchira M. Jha, Bradley J. Molyneaux, Travis C. Jackson, Jessica S. Wallisch, Seo‐Young Park +6 more

Journal of Neurotrauma 2018

Publications

25 total

Duvelisib is a novel NFAT inhibitor that mitigates adalimumab-induced immunogenicity

Aboli Bhingarkar, Yuyin Wang, Keito Hoshitsuki, K. Eichinger, Sanjay Rathod - Frontiers in Pharmacology, 2025

Cited by 0 Semantic Scholar

Additive effects of TPMT and NUDT15 on thiopurine toxicity in children with acute lymphoblastic leukemia across multiethnic populations PDF

Maud Maillard, Rina Nishii, Wenjian Yang, Keito Hoshitsuki, Divyabharathi Chepyala et al. - JNCI Journal of the National Cancer Institute, 2024

Cited by 34 OpenAlex

Clinical Actionability of the NUDT15 *4 (p.R139H) Allele and Its Association With Hispanic Ethnicity

Maud Maillard, Jenny Q Nguyen, Wenjian Yang, Keito Hoshitsuki, M. Relling - Clinical pharmacology and therapy, 2024

Cited by 4 Semantic Scholar

Asparaginase-specific basophil recognition and activation predict Asparaginase hypersensitivity in mice. OA

Sanjay Rathod, Keito Hoshitsuki, Yin Zhu, M. Ramsey, Christian A. Fernandez - Frontiers in Immunology, 2024

Cited by 2 Semantic Scholar

Induction of Cyp2e1 contributes to asparaginase-induced hepatocyte sensitization to lipotoxicity OA

Yin Zhu, Yuyin Wang, Keito Hoshitsuki, Da Yang, Lauren E. Kokai - Acta Pharmaceutica Sinica B, 2024

Cited by 1 Semantic Scholar

Rituximab administration in pediatric patients with newly diagnosed acute lymphoblastic leukemia PDF

Keito Hoshitsuki, Yinmei Zhou, April Miller, John Choi, Hope D. Swanson et al. - Leukemia, 2023

Cited by 10 OpenAlex

Asparagine depletion by the antileukemic agent PEGylated asparaginase induces hepatic stellate cell activation and fibrosis OA

Yi Zhu, Keito Hoshitsuki, Christian Fernandez - ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology, 2023

Cited by 0 Semantic Scholar

Association of Inherited Genetic Factors With Drug-Induced Hepatic Damage Among Children With Acute Lymphoblastic Leukemia PDF

Wenjian Yang, Seth E. Karol, Keito Hoshitsuki, Shawn Lee, Eric Larsen et al. - JAMA Network Open, 2022

Cited by 22 OpenAlex

Long‐read HiFi sequencing of NUDT15 : Phased full‐gene haplotyping and pharmacogenomic allele discovery PDF

Erick R. Scott, Yao Yang, Mariana Rodrigues Botton, Yoshinori Seki, Keito Hoshitsuki et al. - Human Mutation, 2022

Cited by 10 OpenAlex

Long‐read HiFi sequencing of NUDT15: Phased full‐gene haplotyping and pharmacogenomic allele discovery OA

Erick R. Scott, Yao Yang, M. Botton, Yoshinori Seki, Keito Hoshitsuki - Human Mutation, 2022

Cited by 9 Semantic Scholar

Research Topics

Acute Lymphoblastic Leukemia research (11) Folate and B Vitamins Research (4) Childhood Cancer Survivors' Quality of Life (4) Epigenetics and DNA Methylation (3) Acute Myeloid Leukemia Research (3)

Frequent Co-Authors

Jun J. Yang

8 joint publications

Wenjian Yang

6 joint publications

Mary V. Relling

6 joint publications

Takaya Moriyama

4 joint publications

Rina Nishii

4 joint publications

Ching‐Hon Pui

4 joint publications

Affiliations

St. Jude Children's Research Hospital

US 2024 - 2016

University of Pittsburgh

US 2025 - 2016

PharmacoGenetics (China)

CN 2021 - 2021

External Profiles

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Keito Hoshitsuki

Publication & Citation Trends

Most Cited Works

Publications

Duvelisib is a novel NFAT inhibitor that mitigates adalimumab-induced immunogenicity

Additive effects of TPMT and NUDT15 on thiopurine toxicity in children with acute lymphoblastic leukemia across multiethnic populations PDF

Clinical Actionability of the NUDT15 *4 (p.R139H) Allele and Its Association With Hispanic Ethnicity

Asparaginase-specific basophil recognition and activation predict Asparaginase hypersensitivity in mice. OA

Induction of Cyp2e1 contributes to asparaginase-induced hepatocyte sensitization to lipotoxicity OA

Rituximab administration in pediatric patients with newly diagnosed acute lymphoblastic leukemia PDF

Asparagine depletion by the antileukemic agent PEGylated asparaginase induces hepatic stellate cell activation and fibrosis OA

Association of Inherited Genetic Factors With Drug-Induced Hepatic Damage Among Children With Acute Lymphoblastic Leukemia PDF

Long‐read HiFi sequencing of <i>NUDT15</i> : Phased full‐gene haplotyping and pharmacogenomic allele discovery PDF

Long‐read HiFi sequencing of NUDT15: Phased full‐gene haplotyping and pharmacogenomic allele discovery OA

Research Topics

Frequent Co-Authors

Affiliations

External Profiles

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