A. Pacitto

University of Cambridge GB

Publications

423

Citations

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Publication & Citation Trends

Publications

15 total

Synthesis and Structure–Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH PDF

Vinayak Singh, A. Pacitto, Stefano Donini, Davide M. Ferraris, Sándor Boros et al. - European Journal of Medicinal Chemistry, 2019

Cited by 34 OpenAlex

Covalent inactivation of Mycobacterium thermoresistibile inosine-5′-monophosphate dehydrogenase (IMPDH) PDF

Ana Trapero, A. Pacitto, Daniel Shiu‐Hin Chan, Chris Abell, Tom L. Blundell et al. - Bioorganic & Medicinal Chemistry Letters, 2019

Cited by 4 OpenAlex

Fragment-Based Approach to Targeting Inosine-5′-monophosphate Dehydrogenase (IMPDH) from <i>Mycobacterium tuberculosis</i> PDF

Ana Trapero, A. Pacitto, Vinayak Singh, Mohamad Sabbah, Anthony G. Coyne et al. - Journal of Medicinal Chemistry, 2018

Cited by 61 OpenAlex

The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis PDF

Vinayak Singh, Stefano Donini, A. Pacitto, Claudia Sala, Ruben C. Hartkoorn et al. - ACS Infectious Diseases, 2016

Cited by 99 OpenAlex

Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against<i>Mycobacterium tuberculosis</i>

Yumi Park, A. Pacitto, Tracy Bayliss, Laura A. T. Cleghorn, Zhe Wang et al. - ACS Infectious Diseases, 2016

Cited by 91 OpenAlex

Lst4, the yeast Fnip1/2 orthologue, is a DENN-family protein PDF

A. Pacitto, David B. Ascher, Louise H. Wong, Beata K. Blaszczyk, Ravi K. Nookala et al. - Open Biology, 2015

Cited by 29 OpenAlex

Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer PDF

Ravi K. Nookala, Lars Langemeyer, A. Pacitto, Bernardo Ochoa‐Montaño, Jane C. Donaldson et al. - Open Biology, 2012

Cited by 105 OpenAlex

Research Topics

Biochemical and Molecular Research (5) Melanoma and MAPK Pathways (4) Peptidase Inhibition and Analysis (4) Tuberculosis Research and Epidemiology (3) Cytomegalovirus and herpesvirus research (3)

Affiliations

University of Cambridge

GB 2019 - 2012

Bridge University

SS 2016 - 2016

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A. Pacitto

Publication & Citation Trends

Publications

Synthesis and Structure–Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH PDF

Covalent inactivation of Mycobacterium thermoresistibile inosine-5′-monophosphate dehydrogenase (IMPDH) PDF

Fragment-Based Approach to Targeting Inosine-5′-monophosphate Dehydrogenase (IMPDH) from <i>Mycobacterium tuberculosis</i> PDF

The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis PDF

Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against<i>Mycobacterium tuberculosis</i>

Lst4, the yeast Fnip1/2 orthologue, is a DENN-family protein PDF

Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer PDF

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