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KB

K Brocklehurst

Independent Researcher

239

Publications

5,751

Citations

42

H-Index

135

i10-Index

0

2yr Mean Cite

-

Cite/Paper

Data combined from OpenAlex . OA = OpenAlex S2 = Semantic Scholar

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Publication & Citation Trends

Most Cited Works

Covalent chromatography. Preparation of fully active papain from dried papaya latex OA

K Brocklehurst, Jan Carlsson, M. Kierstan, E. M. Crook

Biochemical Journal 1973

253

The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: A kinetic analysis of the inhibition of gelatinase A

Frances Willenbrock, Thomas Crabbe, Patrick M. Slocombe, Chris W. Sutton, Andrew Docherty +5 more

Biochemistry 1993

236

A reporter group delivery system with both absolute and selective specificity for thiol groups and an improved fluorescent probe containing the 7-nitrobenzo-2-oxa-1,3-diazole moiety OA

T. Stuchbury, M Shipton, Roger D. Norris, J. Paul G. Malthouse, K Brocklehurst +2 more

Biochemical Journal 1975

204

Deformed Lattice Detection in Real-World Images Using Mean-Shift Belief Propagation

Minwoo Park, K Brocklehurst, Robert T. Collins, Yanxi Liu

IEEE Transactions on Pattern Analysis and Machine Intelligence 2009

164

Reactions of papain and of low-molecular-weight thiols with some aromatic disulphides. 2,2′-Dipyridyl disulphide as a convenient active-site titrant for papain even in the presence of other thiols OA

K Brocklehurst, G. Little

Biochemical Journal 1973

161

Publications

239 total

Deformed Lattice Detection in Real-World Images Using Mean-Shift Belief Propagation

Minwoo Park, K Brocklehurst, Robert T. Collins, Yanxi Liu - IEEE Transactions on Pattern Analysis and Machine Intelligence, 2009

Cited by 164 OpenAlex

Molecular basis of the activity of the phytopathogen pectin methylesterase PDF

Markus Fries, Jessica Ihrig, K Brocklehurst, Vladimir E. Shevchik, Richard W. Pickersgill - The EMBO Journal, 2007

Cited by 143 OpenAlex

Biochemical and X‐ray crystallographic studies on shikimate kinase: The important structural role of the P‐loop lysine PDF

Tino Krell, John Maclean, Deborah J. Boam, Alan Cooper, Marina Resmini et al. - Protein Science, 2001

Cited by 76 OpenAlex

A Classical Enzyme Active Center Motif Lacks Catalytic Competence until Modulated Electrostatically

Surapong Pinitglang, Aaron Watts, Manij Patel, J. David Reid, Michael A. Noble et al. - Biochemistry, 1997

Cited by 100 OpenAlex

The House Dust Mite AllergenDer p1 Catalytically Inactivates α1-Antitrypsin by Specific Reactive Centre Loop Cleavage: A Mechanism That Promotes Airway Inflammation and Asthma

Noor Kalsheker, S. Deam, Louise Chambers, Suneal K. SREEDHARAN, K Brocklehurst et al. - Biochemical and Biophysical Research Communications, 1996

Cited by 94 OpenAlex

The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: A kinetic analysis of the inhibition of gelatinase A

Frances Willenbrock, Thomas Crabbe, Patrick M. Slocombe, Chris W. Sutton, Andrew Docherty et al. - Biochemistry, 1993

Cited by 236 OpenAlex

Characterization of protein kinase C and its role in catecholamine secretion from bovine adrenal-medullary cells PDF

K Brocklehurst, Kazumasa Morita, Harvey B. Pollard - Biochemical Journal, 1985

Cited by 79 OpenAlex

Specific covalent modification of thiols: Applications in the study of enzymes and other biomolecules

K Brocklehurst - International Journal of Biochemistry, 1979

Cited by 118 OpenAlex

A necessary modification to the preparation of papain from any high-quality latex of <i>Carica papaya</i> and evidence for the structural integrity of the enzyme produced by traditional methods PDF

B S Baines, K Brocklehurst - Biochemical Journal, 1979

Cited by 71 OpenAlex

A convenient method of preparation of high-activity urease from <i>Canavalia ensiformis</i> by covalent chromatography and an investigation of its thiol groups with 2,2'-dipyridyl disulphide as a thiol titrant and reactivity probe PDF

Roger D. Norris, K Brocklehurst - Biochemical Journal, 1976

Cited by 80 OpenAlex

Research Topics

Peptidase Inhibition and Analysis (26) Carbohydrate Chemistry and Synthesis (21) Chemical Synthesis and Analysis (20) Monoclonal and Polyclonal Antibodies Research (20) Protease and Inhibitor Mechanisms (16)

Frequent Co-Authors

JA

Jan Carlsson

2 joint publications

M.

M. Kierstan

2 joint publications

E.

E. M. Crook

2 joint publications

RO

Roger D. Norris

2 joint publications

G.

G. Little

2 joint publications

SU

Suneal K. SREEDHARAN

2 joint publications

Affiliations

University of East Anglia

GB 1998 - 1998

University of London

GB 1998 - 1973

Dalhousie University

CA 1993 - 1993

National Institutes of Health

US 1991 - 1984

St Bartholomew's Hospital

GB 1990 - 1967

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