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DS

Dave Sprengers

Erasmus MC NL

ORCID iD 0000-0003-4280-4210
146
Publications
5,145
Citations
42
H-Index
80
i10-Index
4.67
2yr Mean Cite
-
Cite/Paper
Data combined from OpenAlex . OA = OpenAlex S2 = Semantic Scholar
Verify on Google Scholar

Publication & Citation Trends

Most Cited Works

Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas
Guoying Zhou, Dave Sprengers, Patrick P.C. Boor, Michail Doukas, Hannah M. Schutz +11 more
Gastroenterology 2017
426
Functional impairment of myeloid and plasmacytoid dendritic cells of patients with chronic hepatitis B OA
Renate G. van der Molen, Dave Sprengers, Rekha S. Binda, Esther C. de Jong, Hubert G.M. Niesters +3 more
Hepatology 2004
264
TIGIT, the Next Step Towards Successful Combination Immune Checkpoint Therapy in Cancer OA
Zhouhong Ge, Maikel P. Peppelenbosch, Dave Sprengers, Jaap Kwekkeboom
Frontiers in Immunology 2021
215
Modeling rotavirus infection and antiviral therapy using primary intestinal organoids
Yuebang Yin, Marcel J. C. Bijvelds, Wen Dang, Lei Xu, Annemiek A. van der Eijk +14 more
Antiviral Research 2015
212
Cancer-Associated Fibroblasts Provide a Stromal Niche for Liver Cancer Organoids That Confers Trophic Effects and Therapy Resistance OA
Jiaye Liu, Pengfei Li, Ling Wang, Meng Li, Zhouhong Ge +17 more
Cellular and Molecular Gastroenterology and Hepatology 2020
200

Publications

146 total

TIGIT, the Next Step Towards Successful Combination Immune Checkpoint Therapy in Cancer PDF

Zhouhong Ge, Maikel P. Peppelenbosch, Dave Sprengers, Jaap Kwekkeboom - Frontiers in Immunology, 2021
Cited by 215 OpenAlex

An Engineered IL15 Cytokine Mutein Fused to an Anti-PD1 Improves Intratumoral T-cell Function and Antitumor Immunity PDF

Yuanming Xu, Lucia Campos Carrascosa, Yik A. Yeung, Matthew Ling-Hon Chu, Wenjing Yang et al. - Cancer Immunology Research, 2021
Cited by 97 OpenAlex

Cancer-Associated Fibroblasts Provide a Stromal Niche for Liver Cancer Organoids That Confers Trophic Effects and Therapy Resistance PDF

Jiaye Liu, Pengfei Li, Ling Wang, Meng Li, Zhouhong Ge et al. - Cellular and Molecular Gastroenterology and Hepatology, 2020
Cited by 200 OpenAlex

Mitochondrial Fusion Via OPA1 and MFN1 Supports Liver Tumor Cell Metabolism and Growth PDF

Meng Li, Ling Wang, Yijin Wang, Shaoshi Zhang, Guoying Zhou et al. - Cells, 2020
Cited by 128 OpenAlex

LGR5 marks targetable tumor-initiating cells in mouse liver cancer PDF

Wanlu Cao, Meng Li, Jiaye Liu, Shaoshi Zhang, Lisanne Noordam et al. - Nature Communications, 2020
Cited by 90 OpenAlex

Reduction of immunosuppressive tumor microenvironment in cholangiocarcinoma by ex vivo targeting immune checkpoint molecules

Guoying Zhou, Dave Sprengers, Shanta Mancham, Remco Erkens, Patrick P.C. Boor et al. - Journal of Hepatology, 2019
Cited by 126 OpenAlex

Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas

Guoying Zhou, Dave Sprengers, Patrick P.C. Boor, Michail Doukas, Hannah M. Schutz et al. - Gastroenterology, 2017
Cited by 426 OpenAlex

PD-L1, Galectin-9 and CD8<sup>+</sup> tumor-infiltrating lymphocytes are associated with survival in hepatocellular carcinoma PDF

Kostandinos Sideras, Katharina Biermann, Joanne Verheij, R. Bart Takkenberg, Shanta Mancham et al. - OncoImmunology, 2017
Cited by 130 OpenAlex

Hepatitis E Virus Infects Neurons and Brains PDF

Xinying Zhou, Fen Huang, Lei Xu, Zhanmin Lin, Femke M.S. de Vrij et al. - The Journal of Infectious Diseases, 2017
Cited by 115 OpenAlex

Multiple biopsy passes and the risk of complications of percutaneous liver biopsy

Heng Chi, Bettina E. Hansen, Wing Yin Tang, Jeoffrey Schouten, Dave Sprengers et al. - European Journal of Gastroenterology & Hepatology, 2016
Cited by 96 OpenAlex

Research Topics

Hepatocellular Carcinoma Treatment and Prognosis (31) Hepatitis C virus research (30) Liver Disease Diagnosis and Treatment (29) Immunotherapy and Immune Responses (28) Hepatitis B Virus Studies (25)

Frequent Co-Authors

JA
Jaap Kwekkeboom
11 joint publications
QI
Qiuwei Pan
8 joint publications
JA
Jan N.M. IJzermans
8 joint publications
MA
Maikel P. Peppelenbosch
7 joint publications
GU
Guoying Zhou
5 joint publications
PA
Patrick P.C. Boor
5 joint publications

Affiliations

University of North Carolina at Chapel Hill
US 2004 - 2004
Brigham and Women's Hospital
US 2009 - 2008
Harvard University
US 2009 - 2008
Royal Free London NHS Foundation Trust
GB 1990 - 1990
University of Groningen
NL 2000 - 2000

External Profiles

OpenAlex Profile Search Semantic Scholar ORCID Profile Google Scholar

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