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Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia

Eliza Yankova, Wesley Blackaby, Mark R. Albertella, Justyna Rak, Étienne De Braekeleer, Georgia Tsagkogeorga, Ewa S. Pilka, Demetrios Aspris, Dan Leggate, Alan G. Hendrick, Natalie Webster, Byron Andrews, Richard Fosbeary, Patrick Guest, Nerea Irigoyen, Maria Eleftheriou, Malgorzata Gozdecka, João M.L. Dias, Andrew J. Bannister, Binje Vick, Irmela Jeremias, George S. Vassiliou, Oliver Rausch, Konstantinos Tzelepis, Tony Kouzarides

Nature, 2021

University of Cambridge, Wellcome Sanger Institute, Wellcome/MRC Cambridge Stem Cell Institute, Evotec (United Kingdom), Center for the Study of Childhood and Adolescence, MRC Cancer Unit, Hutchison/MRC Research Centre, The Gurdon Institute, Helmholtz Zentrum München, Ludwig-Maximilians-Universität München, Mission Therapeutics (United Kingdom), Jenner Institute

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