Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials

Merryn Voysey, Sue Ann Costa Clemens, Shabir A. Madhi, Lily Yin Weckx, Pedro M. Folegatti, Parvinder K. Aley, Brian Angus, Vicky L. Baillie, Shaun Barnabas, Qasim Bhorat, Sagida Bibi, Carmen Briner, Paola Cicconi, Elizabeth Clutterbuck, Andrea M. Collins, Clare Cutland, Thomas C. Darton, Keertan Dheda, Christina Dold, C.J. Duncan, Katherine R. W. Emary, Katie Ewer, Amy Flaxman, Lee Fairlie, Saul N. Faust, Shuo Feng, Daniela M. Ferreira, Adam Finn, Eva Galiza, Anna L. Goodman, Catherine Green, Christopher Green, Melanie Greenland, Catherine Hill, Helen Hill, Ian Hirsch, Alane Izu, Daniel Jenkin, Carina C. D. Joe, Simon Kerridge, Anthonet Koen, Gaurav Kwatra, Rajeka Lazarus, Vincenzo Libri, Patrick Lillie, Natalie G. Marchevsky, Richard P. Marshall, Ana Verena Almeida Mendes, Eveline Pı́polo Milan, Angela M. Minassian, Alastair McGregor, Yama F Mujadidi, Anusha Nana, Sherman D. Padayachee, Daniel J. Phillips, Ana Maria Pittella, Emma Plested, Katrina M. 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Taylor, Justin Taylor, Rebecca te Water Naudé, Kate Templeton, Yrene Themistocleous, Andreas C. Themistocleous, Merin Thomas, Kelly Thomas, Tonia M. Thomas, Asha Thombrayil, Julia Thompson, Fawziyah Thompson, Ameeka Thompson, Amber Thompson, Kevin Thompson, V Thornton-Jones, Larissa H.S. Thotusi, Patrick J. Tighe, Lygia Accioly Tinoco, Gerlynn Tiongson, Bonolo Tladinyane, Michele Tomasicchio, Adriana Tomić, Susan Tonks, James Towner, Nguyen Tran, Julia A. Tree, Gerry Trillana, Charlotte Trinham, Rose Trivett, Adam Truby, Betty Lebogang Tsheko, Philippa Tubb, Aadil Turabi, Richard Turner, Cheryl Turner, Nicola Turner, Bhavya Tyagi, Marta Ulaszewska, Benjamin R. Underwood, Samual van Eck, Rachel Varughese, Dennis Verbart, Marije K. Verheul, Iason Vichos, Taiane Alves Vieira, Gemma Walker, Laura Walker, Matthew E. Wand, T. M. Wardell, George M. 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The Lancet, 2021