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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

the Million Veteran Program, Εvangelos Εvangelou, Helen R. Warren, David Mosén-Ansorena, Borbála Mifsud, Raha Pazoki, He Gao, Georgios Ntritsos, Niki Dimou, Claudia P. Cabrera, İbrahim Karaman, Fu Liang Ng, Marina Evangelou, Katarzyna Witkowska, Evan Tzanis, Jacklyn N. Hellwege, Ayush Giri, Digna R. Velez Edwards, Yan V. Sun, Kelly Cho, J. Michael Gaziano, Peter W.F. Wilson, Philip S. Tsao, Csaba P. Kövesdy, Tõnu Esko, Reedik Mägi, Lili Milani, Peter Almgren, Thibaud Boutin, Stéphanie Debette, Jun Ding, Franco Giulianini, Elizabeth Holliday, Anne Jackson, Ruifang Li‐Gao, Wei‐Yu Lin, Jian’an Luan, Massimo Mangino, Christopher Oldmeadow, Bram P. Prins, Yong Qian, Muralidharan Sargurupremraj, Nabi Shah, Praveen Surendran, Sébastien Thériault, Niek Verweij, Sara M. Willems, Jing-Hua Zhao, Philippe Amouyel, John Connell, Renée de Mutsert, Alex S. F. Doney, Martin Farrall, Cristina Menni, Andrew D. Morris, Raymond Noordam, Guillaume Paré, Neil R Poulter, Denis C. Shields, Alice Stanton, Simon Thom, Gonçalo Abecasis, Najaf Amin, Dan E. Arking, Kristin L. Ayers, Caterina Barbieri, Chiara Batini, Joshua C. Bis, Tineka Blake, Murielle Bochud, Michael Boehnke, Eric Boerwinkle, Dorret I. Boomsma, Erwin P. Böttinger, Peter S. Braund, Marco Brumat, Archie Campbell, Harry Campbell, Aravinda Chakravarti, John C. Chambers, Ganesh Chauhan, Marina Ciullo, Massimiliano Cocca, Francis S. Collins, Heather J. Cordell, Gail Davies, Martin H. de Borst, Eco J. C. de Geus, Ian J. Deary, Joris Deelen, Fabiola Del Greco M, Cumhur Yusuf Demirkale, Marcus Dörr, Georg Ehret, Roberto Elosúa, Stefan Enroth, A. Mesut Erzurumluoglu, Teresa Ferreira, Mattias Frånberg, Oscar H. Franco, Ilaria Gandin, Paolo Gasparini, Vilmantas Giedraitis, Christian Gieger, Giorgia Girotto, Anuj Goel, Alan J. Gow, Vilmundur Guðnason, Xiuqing Guo, Ulf Gyllensten, Anders Hamsten, Tamara B. Harris, Sarah E. Harris, Catharina A. Hartman, Aki S. Havulinna, Andrew A. Hicks, Edith Hofer, Albert Hofman, Jouke‐Jan Hottenga, Jennifer E. Huffman, Shih-Jen Hwang, Erik Ingelsson, Alan James, Rick Jansen, Marjo‐Riitta Järvelin, Roby Joehanes, Åsa Johansson, Andrew D. Johnson, Peter K. Joshi, Pekka Jousilahti, J. Wouter Jukema, Antti Jula, Mika Kähönen, Sekar Kathiresan, Bernard Keavney, Kay‐Tee Khaw, Paul Knekt, Jo Knight, Ivana Kolčić, Jaspal S. Kooner, Seppo Koskinen, Kati Kristiansson, Zoltán Kutalik, Maris Laan, Marty Larson, Lenore J. Launer, Benjamin Lehne, Terho Lehtimäki, David C. Liewald, Li Lin, Lars Lind, Cecilia M. Lindgren, YongMei Liu, Ruth J. F. Loos, Lorna M. Lopez, Yingchang Lu, Leo‐Pekka Lyytikäinen, Anubha Mahajan, Chrysovalanto Mamasoula, Jaume Marrugat, Jonathan Marten, Yuri Milaneschi, Anna Morgan, Andrew P. Morris, Alanna C. Morrison, Peter J. Munson, Mike A. Nalls, Priyanka Nandakumar, Christopher P. Nelson, Teemu Niiranen, Ilja M. Nolte, Teresa Nutile, Albertine J. Oldehinkel, Ben A. Oostra, Paul F. O’Reilly, Elin Org, Sandosh Padmanabhan, Walter Palmas, Aarno Palotie, Alison Pattie, Brenda W.J.H. Penninx, Markus Perola, Annette Peters, Ozren Polašek, Peter P. Pramstaller, Quang Tri Nguyen, Olli T. Raitakari, Meixia Ren, Rainer Rettig, Kenneth Rice, Paul M. Ridker, Janina S. Ried, Harriëtte Riese, Samuli Ripatti, Antonietta Robino, Lynda M. Rose, Jerome I. Rotter, Igor Rudan, Daniela Ruggiero, Yasaman Saba, Cinzia Sala, Veikko Salomaa, Nilesh J. Samani, Antti-Pekka Sarin, Reinhold Schmidt, Helena Schmidt, Nick Shrine, David Siscovick, Albert V. Smith, Harold Snieder, Siim Sõber, Rossella Sorice, John M. Starr, David J. Stott, David P. Strachan, Rona J. Strawbridge, Johan Sundström, Morris A. Swertz, Kent D. Taylor, Alexander Teumer, Martin D. Tobin, Maciej Tomaszewski, Daniela Toniolo, Michela Traglia, Stella Trompet, Jaakko Tuomilehto, Christophe Tzourio, André G. Uitterlinden, Ahmad Vaez, Peter J. van der Most, Cornelia M. van Duijn, Anne‐Claire Vergnaud, Germaine C. Verwoert, Véronique Vitart, Uwe Völker, Péter Vollenweider, Dragana Vuckovic, Hugh Watkins, Sarah H. Wild, Gonneke Willemsen, James F. Wilson, Alan F. Wright, Jie Yao, Tatijana Zemunik, Weihua Zhang, John Attia, Adam S. Butterworth, Daniel I. Chasman, David Conen, Francesco Cucca, John Danesh, Caroline Hayward, Joanna M. M. Howson, Markku Laakso, Edward G. Lakatta, Claudia Langenberg, Olle Melander, Dennis O. Mook‐Kanamori, Colin N. A. Palmer, Lorenz Risch, Robert A. Scott, Rodney J. Scott, Peter Sever, Tim D. Spector, Pim van der Harst, Nicholas J. Wareham, Eleftheria Zeggini, Daniel Levy, Patricia B. Munroe, Christopher Newton‐Cheh, Morris J. Brown, Andres Metspalu, Adriana M. Hung, Christopher J. O’Donnell, Todd L. Edwards, Bruce M. Psaty, Ioanna Tzoulaki, Michael R. Barnes, Louise V. Wain, Paul Elliott, Mark J. Caulfield

Nature Genetics, 2018

Imperial College London, Queen Mary University of London, University of Ioannina, William Harvey Research Institute, National Institute for Health and Care Research, VA Tennessee Valley Healthcare System, Vanderbilt University Medical Center, Valley Health System, Vanderbilt Health, Emory University, VA Boston Healthcare System, Brigham and Women's Hospital, Emory Clinic, Atlanta VA Medical Center, VA Palo Alto Health Care System, Stanford University, University of Tennessee Health Science Center, Memphis VA Medical Center, University of Tartu, Broad Institute, Malmö University, Lund University, Western General Hospital, Institute of Genetics and Cancer, Université de Bordeaux, Inserm, Bordeaux Population Health, Hunter Medical Research Institute, University of Michigan, Statistical Research (United States), Leiden University Medical Center, University of Cambridge, MRC Epidemiology Unit, King's College London, Guy's and St Thomas' NHS Foundation Trust, Wellcome Sanger Institute, University of Dundee, COMSATS University Islamabad, McMaster University, Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval, University Medical Center Groningen, University of Groningen, Massachusetts General Hospital, Center for Human Genetics, Université de Lille, Institut Pasteur de Lille, Ninewells Hospital, Centre for Human Genetics, University of Oxford, University of Edinburgh, University of Liverpool, MRC Clinical Trials Unit at UCL, University College Dublin, Royal College of Surgeons in Ireland, Erasmus MC, Erasmus University Rotterdam, Johns Hopkins University, Johns Hopkins Medicine, Newcastle University, Sema4 (United States), University of Leicester, University of Washington, University Hospital of Lausanne, Institute of Social and Preventive Medicine, Baylor College of Medicine, The University of Texas Health Science Center at Houston, Vrije Universiteit Amsterdam, Icahn School of Medicine at Mount Sinai, University of Trieste, Glenfield Hospital, NIHR Leicester Biomedical Research Centre, Edinburgh Cancer Research, Imperial College Healthcare NHS Trust, Nanyang Technological University, Ealing Hospital, Indian Institute of Science Bangalore, Institute of Genetics and Biophysics, IRCCS Materno Infantile Burlo Garofolo, Istituto Neurologico Mediterraneo, National Human Genome Research Institute, Eurac Research, Institute for Biomedicine, University of Lübeck, National Institutes of Health, Center for Information Technology, Universitätsmedizin Greifswald, German Centre for Cardiovascular Research, Centro de Investigación en Red en Enfermedades Cardiovasculares, University Hospital of Geneva, Universitat de Vic - Universitat Central de Catalunya, Science for Life Laboratory, Karolinska Institutet, Health Data Research UK, Karolinska University Hospital, Stockholm University, Helmholtz Zentrum München, Deutsches Diabetes-Zentrum e.V., German Center for Diabetes Research, Heinrich Heine University Düsseldorf, University of Iceland, Heriot-Watt University, The Lundquist Institute, UCLA Medical Center, Icelandic Heart Association, Harbor–UCLA Medical Center, National Institute on Aging, Finnish Institute for Health and Welfare, University of Helsinki, Institute for Molecular Medicine Finland, Medical University of Graz, Harvard University, National Heart Lung and Blood Institute, Framingham Heart Study, Uppsala University, Sir Charles Gairdner Hospital, The University of Western Australia, Amsterdam Neuroscience, Oulu University Hospital, Oulu University of Applied Sciences, University of Oulu, Hebrew SeniorLife, Tampere University Hospital, Tampere University, Tampere University, University of Manchester, Massachusetts Institute of Technology, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust, Lancaster University, University of Split, SIB Swiss Institute of Bioinformatics, Fimlab (Finland), Wake Forest University, Child Health and Development Institute, Beaumont Hospital, GGZ inGeest, Data Tecnica International (United States), University of Turku, Turku University Hospital, Columbia University Irving Medical Center, British Heart Foundation, University of Glasgow, Psychiatric Hospital Sveti Ivan, Ospedale di Bolzano, Fujian Medical University, Fujian Provincial Hospital, New York Academy of Medicine, Alzheimer Scotland, St George's, University of London, Dasman Diabetes Institute, King Abdulaziz University, Isfahan University of Medical Sciences, Sidra Medical and Research Center, Glasgow Centre for Population Health, Genomics (United Kingdom), University Hospital of Basel, Institute of Genetic and Biomedical Research, National Research Council, University of Sassari, University of Eastern Finland, Kuopio University Hospital, University of Liechtenstein, University of Bern, University Hospital of Bern, Private University in the Principality of Liechtenstein, Vanderbilt University, Kaiser Permanente Washington Health Research Institute, NIHR Imperial Biomedical Research Centre, UK Dementia Research Institute

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