Timothy M. Willson

University of North Carolina at Chapel Hill US

0000-0003-4181-8223

418

Publications

68,897

Citations

110

H-Index

226

i10-Index

3.92

2yr Mean Cite

Cite/Paper

Data combined from OpenAlex . OA = OpenAlex S2 = Semantic Scholar

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Publication & Citation Trends

Most Cited Works

An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ) OA

Jürgen M. Lehmann, Linda B. Moore, Tracey Smith-Oliver, William O. Wilkison, Timothy M. Willson +1 more

Journal of Biological Chemistry 1995

3,619

The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

Mercedes Ricote, Andrew C. Li, Timothy M. Willson, Carolyn Kelly, Christopher K. Glass

Nature 1998

3,515

Bile Acids: Natural Ligands for an Orphan Nuclear Receptor

Derek J. Parks, Steven G. Blanchard, Randy K. Bledsoe, Gyan Chandra, Thomas G. Consler +6 more

Science 1999

2,235

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ OA

Steven A. Kliewer, Scott S. Sundseth, Stacey A. Jones, Peter J. Brown, G. Bruce Wisely +6 more

Proceedings of the National Academy of Sciences 1997

2,147

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation OA

Steven A. Kliewer, James M. Lenhard, Timothy M. Willson, Inder Patel, David C. Morris +1 more

Cell 1995

2,023

Publications

417 total

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ PDF

Gabriel Pascual, Amy L. Fong, Sumito Ogawa, Amir Gamliel, Andrew C. Li et al. - Nature, 2005

Cited by 1,218 OpenAlex

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity PDF

Jeff L. Staudinger, Bryan Goodwin, Stacey A. Jones, Diane Hawkins-Brown, Kathleen I. MacKenzie et al. - Proceedings of the National Academy of Sciences, 2001

Cited by 1,345 OpenAlex

A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport PDF

William R. Oliver, Jennifer L. Shenk, Mike R. Snaith, CAROLINE S. RUSSELL, Kelli D. Plunket et al. - Proceedings of the National Academy of Sciences, 2001

Cited by 1,040 OpenAlex

A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis PDF

Bryan Goodwin, Stacey A. Jones, Roger R. Price, Michael A. Watson, David D. McKee et al. - Molecular Cell, 2000

Cited by 1,887 OpenAlex

The PPARs: From Orphan Receptors to Drug Discovery PDF

Timothy M. Willson, Peter J. Brown, Daniel D. Sternbach, Brad R. Henke - Journal of Medicinal Chemistry, 2000

Cited by 1,800 OpenAlex

Bile Acids: Natural Ligands for an Orphan Nuclear Receptor

Derek J. Parks, Steven G. Blanchard, Randy K. Bledsoe, Gyan Chandra, Thomas G. Consler et al. - Science, 1999

Cited by 2,235 OpenAlex

Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors PDF

H. Eric Xu, Millard H. Lambert, Valerie G. Montana, Derek J. Parks, Steven G. Blanchard et al. - Molecular Cell, 1999

Cited by 1,159 OpenAlex

The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

Mercedes Ricote, Andrew C. Li, Timothy M. Willson, Carolyn Kelly, Christopher K. Glass - Nature, 1998

Cited by 3,515 OpenAlex

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ

Robert T. Nolte, G. Bruce Wisely, Stefan Westin, Jeffery E. Cobb, Millard H. Lambert et al. - Nature, 1998

Cited by 1,941 OpenAlex

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. PDF

J�rgen Lehmann, David D. McKee, M. A. Watson, Timothy M. Willson, John T. Moore et al. - Journal of Clinical Investigation, 1998

Cited by 1,563 OpenAlex

Research Topics

Peroxisome Proliferator-Activated Receptors (98) Estrogen and related hormone effects (60) Drug Transport and Resistance Mechanisms (57) Cholesterol and Lipid Metabolism (44) Computational Drug Discovery Methods (41)

Frequent Co-Authors

Steven A. Kliewer

11 joint publications

JÜ

Jürgen M. Lehmann

7 joint publications

Stacey A. Jones

4 joint publications

Linda B. Moore

3 joint publications

Christopher K. Glass

3 joint publications

Peter J. Brown

3 joint publications

Affiliations

Dartmouth College

US 2001 - 2000

University of North Carolina at Chapel Hill

US 2025 - 2015

Novartis (Switzerland)

CH 2015 - 2015

National Institutes of Health

US 2006 - 2006

Society for Neuroscience

US 2003 - 2003

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Timothy M. Willson

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